The world number 19 was a semifinalist at the Australian Open in 2008 and broke into the top 10 when she reached number 5 in August 2002.
She will be joined by French Open Champion Ana Ivanovic and reigning Australian Women’s Hardcourt Champion Na Li in the women’s draw.
The men’s draw boasts Novak Djokovic, Jo-Wilfried Tsonga, Marcos Baghdatis, Gael Monfils, Richard Gasquet and Mardy Fish with the player cut off date, for the tournament ,on the 21 November.
Daniela Hantuchova said “I am really excited about returning to Australia and playing a strong field in the lead up to the Grand Slam.
“I took home some really nice memories last year. It was something very special for me.
“With my preparation this year and the quality field at the Brisbane International, I will be even more ready.
“I love Australia and have played in tournaments there since 2001. I am looking forward to playing in this new event and challenging some high quality players in the lead up to the Australian Open.”